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apalutamide will decrease the level or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with medicine that are CYP2C19 substrates may result in decrease publicity to those prescription drugs.I really like that I have a direct-use seizure med

Watch Intently (one)crofelemer will increase amounts of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Crofelemer has the potential to inhibit CYP3A4 at concentrations predicted inside the intestine; not likely to inhibit systemically mainly because minimally absorbed.diazepam raises amounts of lomitapide by i